A comprehensive literature review of scientific studies among 1995 and 2018 was carried out using the electronic databases PubMed and EBSCO Host. Searches have been performed utilizing the following conditions: complete knee arthroplasty (TKA); cyclooxygenase-two inhibitors; bracing; Actual physical therapy; weight reduction; knee; treatment; therapeutics; OA; intra-articular injectio... https://www.theorthopaedicandpainpractice.com/non-surgical-treatments-for-knee-joint-pain/