Poor oral bioavailability limits chlorogenic acid (CGA) benefits on the gut-brain axis. In this study we demonstrate the existence of an active circadian-dependent efflux for the CGA intestinal permeation. leading to greater bioavailability in the evening rather than in the morning. As therapeutic/nutraceutical polyphenols can mutually influence their intestinal absorption following c... https://www.hindirochakkahaniya.com/