Conolidine’s analgesic results stem from its interaction with non-opioid pain pathways. In contrast to opioids, which bind to µ-opioid receptors from the central anxious process, conolidine modulates alternate molecular targets. A Science Developments study located that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. https://how-to-use-conolidine31616.sharebyblog.com/37998149/5-simple-techniques-for-conolidin-to-replace-traditional-painkillers